[Retracted] Single-Cell Transcriptome Analysis Reveals the Importance of IRF1/FSTL1 in Synovial Fibroblast Subsets for the Development of Rheumatoid Arthritis

Figure 5

Comparison of regulon between the RA and OA groups. (a) In the SCENIC analysis, tSNE of the distribution of SF subset 1 between the RA and OA groups. (b–c) The top 5 regulons and IRF1 regulon of both RA and OA groups are ranked based on the RSS ranking position. (d) Regulatory status of the IRF1 regulon in single cells. (e–f) Analysis of gene expression differences between RA and OA groups at the single-cell level. Yellow dots represent genes up-regulated in RA and dark blue dots represent genes up-regulated in OA. Large diameter dots represent genes that are differentially expressed between the two groups. (g) The tSNE of the distribution of SF subset 2 between the RA and OA groups. (h–i) The top 5 regulons and IRF1 regulon of both RA and OA groups were ranked based on the RSS ranking position.

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