Efficacy of Low Molecular Weight Heparin in Preventing Perinatal Venous Thrombosis: A Meta-Analysis

Table 1

Basic characteristics and Jadad score of included literature.

Author	Year	No. of patients		Study type	Intervention		Outcomes	Jadad
		LMWH	Control		LMWH	Control
Badawy et al. [21]	2008	170	170	RCT	Enoxaparin sodium (0.2 ml, once daily) + folic acid tablets (0.5 mg daily)	Folic acid tablets (0.5 mg daily)	Hemorrhage	6
Bi [22]	2017	45	45	RCT	LMWH sodium (twice daily) + PT	PT	Postpartum VT	4
Burrows et al. [23]	2001	39	37	RCT	Dalteparin (2,500 IU, once daily)	Normal sodium	Postpartum VT; hemorrhage	6
Gates et al. [24]	2004	78	79	RCT	Enoxaparin (40 mg, once daily)	Placebo (1 ml, once daily)	Perinatal VT; hemorrhage	7
Huang [20]	2018	31	31	RCT	LMWH sodium (200 U/kg, once daily) + PT	PT	Perinatal VT	4
Li et al. [25]	2018	51	51	RCT	Enoxaparin (40 mg, once daily) + obstetrical care	Obstetrical care	Postpartum VT	3
Lin et al. [26]	2021	58	58	RCT	LMWH sodium (5000 U/kg, once daily)	Conventional therapy	Postpartum VT	4
Liu [27]	2020	32	32	RCT	LMWH sodium (4250 U/kg, twice daily) + PT	PT	Postpartum VT	3
Pettilä et al. [28]	1999	50	50	RCT	Dalteparin once daily (mean 4631 IU/day)	Unfractionated heparin twice daily (20569 IU/day)	Perinatal VT; hemorrhage	5
Rodger et al. [19]	2014	146	143	RCT	Dalteparin: 5000 IU once daily + obstetrical care	Obstetrical care	Perinatal VT; hemorrhage	6
Zhang [29]	2013	58	58	RCT	LMWH sodium (5000 U/kg, twice daily)	Conventional therapy	Postpartum VT	4

Note: LMWH: low molecular weight heparin; RCT: randomized controlled trial; PT: physical therapy; VT: venous thrombosis.