[Retracted] lncRNA MSC-AS1/miRNA-429 Axis Mediates Growth and Metastasis of Nasopharyngeal Carcinoma via JAK1/STAT3 Signaling Pathway

Figure 1

MSC-AS1 and miR-429 levels in NPC tumor tissues and cells. (a) MSC-AS1 expression was detected in tumor and adjacent normal tissues from 80 NPC patients by qRT-PCR analysis. The expression of MSC-AS1 was significantly higher in tumor tissues than in normal ones. (b) Patients were classified into high MSC-AS1 expression and low expression groups based on the median. The survival curve showed that high MSC-AS1 expression was negatively correlated with survival time. (c) The expression of miR-429 was measured in NPC tumor and adjacent normal tissues by qRT-PCR analysis. MiR-429 expression was obviously lower in tumor tissues, compared with normal controls. (d) Pearson analysis was conducted to analyze the correlation between the expression of MSC-AS1 and miR-429. The result showed that MSC-AS1 and miR-429 expression exhibited a negative relationship in NPC tissues. (e) The expression level of MSC-AS1 was detected in NPC cell lines (C666-1, HK-1, and TW01) and normal NP-69 cells. MSC-AS1 expression was significantly increased in NPC cell lines, compared with NP-69. , , and . (f) The expression of miR-429 was detected in NPC cell lines (C666-1, HK-1, and TW01) and normal NP-69 cells by qRT-PCR analysis. miR-429 expression was markedly declined in NPC cell lines. , , and .

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