IRF9 and XAF1 as Diagnostic Markers of Primary Sjogren Syndrome

<div>PPI network of DEGs and three cluster modules extracted by MCODE. (a) The interaction network between proteins coded by DEGs. (b) The interaction between the ten identified hub genes. Each node represents a protein, whereas each edge represents one protein–protein association. The purple rectangles represent the upregulated gene, and the yellow ones represent the downregulated gene. Two cluster modules extracted by MCODE. (c) Cluster 1 had higher cluster score (<span class="nowrap"><svg height="8.98583pt" id="M42" style="vertical-align:-0.2324905pt" version="1.1" viewbox="-0.0498162 -8.75334 119.148 8.98583" width="119.148pt" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink"><g transform="matrix(.013,0,0,-0.013,0,0)"><path d="M861 0V28C774 35 771 41 768 147L759 509C756 612 762 614 851 622V650H681L449 149L221 650H57V622C148 613 153 609 144 479L130 271C123 166 117 123 111 88C104 46 85 34 26 28V0H259V28C192 35 169 42 167 90C166 130 166 173 170 256L185 541H187L411 7H431L675 555H679L683 147C683 41 680 35 598 28V0H861Z"></path></g><g transform="matrix(.013,0,0,-0.013,11.466,0)"><path d="M614 175C564 76 510 21 408 21C256 21 146 149 146 336C146 488 235 629 402 629C510 629 570 586 597 480L626 488C620 541 614 582 606 638C578 643 510 665 429 665C206 665 44 527 44 316C44 157 153 -15 402 -15C474 -15 558 5 586 11C604 45 629 119 643 165L614 175Z"></path></g><g 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Computational and Mathematical Methods in Medicine

IRF9 and XAF1 as Diagnostic Markers of Primary Sjogren Syndrome

Figure 3