[Retracted] MDH1 and MDH2 Promote Cell Viability of Primary AT2 Cells by Increasing Glucose Uptake

Figure 2

The TCA cycle pathway was inactivated in primary AT2 cells of septic-ALI mice. (a) Screening for differentially expressed genes in the peripheral blood of healthy donors () and septic-ALI patients (). (b) KEGG analysis of 3918 downregulated genes and 1372 upregulated genes. (c, d) Expression of ACLY, ACO1, CS, DLAT, DLST, FH, IDH1, IDH3A, MDH1, MDH2, PDHA1,PDHB, SDHA, SUCLA2, and SUCLG2 was detected in the (c) GSE32707 dataset, or in septic-ALI mice () and control mice () via RT-PCR detection in (d) AT2 cells. (e, f) Expression of MDH1 and MDH2 was done via (e) WB assay () and (f) immunofluorescence assay in AT2 cells (). , , .

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