[Retracted] MDH1 and MDH2 Promote Cell Viability of Primary AT2 Cells by Increasing Glucose Uptake

Figure 3

MDH1 or MDH2 promoted the proliferation and invasion of primary AT2 cells by promoting glucose uptake. (a, b) RT-PCR and (c, d) WB were used to detect the effect of siRNA and overexpressed plasmid on AT2 cells. (e) MDH1 or MDH2 promoted the glucose uptake of AT2 cells. (f) The proliferation of AT2 cells was dependent on glucose. (g, h) The effect of MDH1 or MDH2 on the proliferation of AT2 cells was measured in (g) 100% high-glucose medium or (h) 100% glucose-free medium via CCK-8. (i) The effect of MDH1 or MDH2 on the proliferation of AT2 cells was measured via EdU assays in 100% high-glucose medium. (j) The invasion of AT2 cells was dependent on glucose. (k, l) The effect of MDH1 or MDH2 on the invasion of AT2 cells was measured in 100% high-glucose medium (k) or 100% glucose-free medium (l) via transwell assay. , , ; NS: no significance.

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