Research Article

Construction of Pulmonary Nodule CT Radiomics Random Forest Model Based on Artificial Intelligence Software for STAS Evaluation of Stage IA Lung Adenocarcinoma

Table 2

Comparison of preoperative clinical imaging data between the STAS-negative group and STAS-positive group of the stage IA lung adenocarcinoma.

VariableSTAS negative ()STAS positive () value

Sex0.549
 Male31 (42.5%)6 (31.6%)
 Female42 (57.5%)13 (68.4%)
Age53.1 (10.9)56.9 (7.61)0.085
Maximum CT value (Hu)-118.38 (141)49.1 (62.9)<0.001
Minimum CT value (Hu)-553.00 [-659.00, -359.00]-347.00 [-465.50, -203.00]0.001
Mean CT value (Hu)-321.60 [-442.01, -194.00]-106.42 [-133.14, -60.51]<0.001
Variance of CT values (Hu)82.3 [58.4, 132]115 [93.6, 152]0.043
Kurtosis2.40 [2.04, 2.50]2.43 [2.13, 2.48]0.732
Skewness0.78 [0.39, 0.94]-0.75 [-0.84, 0.65]0.006
Maximum section area (mm2)152 [87.6, 231]336 [171, 408]0.004
Superficial area (mm2)679 [378, 1284]1289 [852, 1921]0.005
3D longest diameter (mm)<0.001
Compactness0.025
Sphericity0.041
Entropy8.19 [7.81, 8.57]8.59 [8.38, 8.94]<0.001
Location0.659
 Right upper lobe26 (35.6%)7 (36.8%)
 Right lower lobe18 (24.7%)4 (21.1%)
 Right middle lung5 (6.85%)0 (0.00%)
 Left upper lung16 (21.9%)7 (36.8%)
 Left lower lobe8 (11.0%)1 (5.26%)
Volume (mm3)1641 [703, 2997]3476 [2345, 4167]0.001
CTR0.46 [0.41, 0.49]0.50 [0.49, 0.64]<0.001