[Retracted] Implications of Human Antimicrobial Peptide Defensin Beta-1 in Clinical Oral Squamous Cell Carcinoma Patients via an Integrated Bioinformatics Approach

Figure 7

The biological functions enriched by DEFB1-correlated genes. (a) The functional enrichment analysis results of the significantly correlated genes of DEFB1, in terms of GO terms—BP (biological process); CC (cellular component); MF (molecular function); and KEGG pathways. (b) The results obtained by GSEA, which were visualized by mountain plot and enrichment plot. The mountain plot showed the functional terms obtained by GSEA, according to the criteria of .adjust < 0.05, val < 0.25, and . The enrichment plot showed that DEFB1-significantly correlated genes were mainly enriched in four signaling pathways, ECM (extracellular matrix), RTK (receptor tyrosine kinases)/PI3K/AKT signaling axis, keratinization, and proinflammatory cytokine-related pathways.

(a) Functional enrichment analysis

(b) Gene set enrichment analysis