[Retracted] Implications of Human Antimicrobial Peptide Defensin Beta-1 in Clinical Oral Squamous Cell Carcinoma Patients via an Integrated Bioinformatics Approach

Table 2

The clinical characteristics of the TCGA-OSCC patients depending on the expression level of DEFB1 gene.

Characteristic	Levels	Low expression of DEFB1	High expression of DEFB1
		164	165
T stage, (%)	T1	10 (3.1%)	8 (2.5%)	0.964
	T2	53 (16.6%)	52 (16.3%)
	T3	40 (12.5%)	42 (13.2%)
	T4	57 (17.9%)	57 (17.9%)
N stage, (%)	N0	78 (24.8%)	90 (28.6%)	0.415
	N1	31 (9.8%)	25 (7.9%)
	N2	49 (15.6%)	39 (12.4%)
	N3	1 (0.3%)	2 (0.6%)
M stage, (%)	M0	156 (50%)	154 (49.4%)	1.000
	M1	1 (0.3%)	1 (0.3%)
Clinical stage, (%)	Stage I	6 (1.9%)	5 (1.6%)	0.887
	Stage II	37 (11.6%)	42 (13.2%)
	Stage III	32 (10%)	33 (10.3%)
	Stage IV	85 (26.6%)	79 (24.8%)
Radiation therapy, (%)	No	60 (20.3%)	56 (19%)	0.828
	Yes	89 (30.2%)	90 (30.5%)
Primary therapy outcome, (%)	PD	16 (5.8%)	19 (6.8%)	0.312
	SD	3 (1.1%)	1 (0.4%)
	PR	3 (1.1%)	0 (0%)
	CR	121 (43.5%)	115 (41.4%)
Gender, (%)	Female	49 (14.9%)	53 (16.1%)	0.748
	Male	115 (35%)	112 (34%)
Race, (%)	Asian	3 (0.9%)	6 (1.9%)	0.684
	Black or African American	11 (3.5%)	10 (3.1%)
	White	144 (45.3%)	144 (45.3%)
Age, (%)	≤60	81 (24.7%)	74 (22.6%)	0.442
	>60	82 (25%)	91 (27.7%)
Histologic grade, (%)	G1	17 (5.3%)	35 (10.9%)	0.043
	G2	105 (32.7%)	95 (29.6%)
	G3	36 (11.2%)	31 (9.7%)
	G4	1 (0.3%)	1 (0.3%)
Anatomic neoplasm subdivision, (%)	Alveolar ridge	6 (1.8%)	12 (3.6%)	0.250
	Base of tongue	12 (3.6%)	11 (3.3%)
	Buccal mucosa	14 (4.3%)	8 (2.4%)
	Floor of mouth	33 (10%)	28 (8.5%)
	Hard palate	1 (0.3%)	6 (1.8%)
	Oral cavity	37 (11.2%)	35 (10.6%)
	Oral tongue	61 (18.5%)	65 (19.8%)
Smoker, (%)	No	43 (13.3%)	44 (13.6%)	1.000
	Yes	118 (36.5%)	118 (36.5%)
Alcohol history, (%)	No	41 (12.8%)	64 (19.9%)	0.012
	Yes	118 (36.8%)	98 (30.5%)
Lymphovascular invasion, (%)	No	81 (33.9%)	83 (34.7%)	0.965
	Yes	38 (15.9%)	37 (15.5%)
Lymph node neck dissection, (%)	No	28 (8.6%)	17 (5.2%)	0.104
	Yes	135 (41.3%)	147 (45%)
OS event, (%)	Alive	82 (24.9%)	97 (29.5%)	0.136
	Dead	82 (24.9%)	68 (20.7%)
DSS event, (%)	Alive	105 (33.7%)	114 (36.5%)	0.414
	Dead	50 (16%)	43 (13.8%)
PFI event, (%)	Alive	90 (27.4%)	104 (31.6%)	0.164
	Dead	74 (22.5%)	61 (18.5%)
Age, median (IQR)		61 (52, 71)	62 (55, 69)	0.524