[Retracted] Lentinan Enhances the Function of Oxaliplatin on the Esophageal Tumors by Persuading Immunogenic Cell Death

Figure 3

LNT enhances the sensitivity of EC-109 cells to Oxa. (a) The conjunction of LNT and Oxa greatly reduced EC-109 cell growth (). (b) The combination of LNT and Oxa persuaded programmed cell death in EC-109 cells (). (c) LNT combination and Oxa induced mRNA expression levels of BAX and CASP3 and inhibited the mRNA expression BCL2 () level. (d) The conjunction of LNT and Oxa increased BAX and cleaved caspase 3 protein expression while suppressing BCL2 protein expression (). (e) The analysis of the combination index (CI) of LNT and Oxa using the CompuSyn software revealed that both LNT and Oxa acted synergistically on EC-109 cells. The data were expressed as the mean standard deviation for each experiment, which was done in triplicate. in comparison to 0 g to analyze the differences between groups; statistical analysis using one-way analysis of variance (ANOVA) was used.

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