[Retracted] Lentinan Enhances the Function of Oxaliplatin on the Esophageal Tumors by Persuading Immunogenic Cell Death

Figure 4

LNT-induced immunogenic cell death (ICD) pathway in EC-109 cells enhances the effectiveness of the combined Oxa intervention. (a) LNT alone or combined with Oxa induced the release of ATP, CXCL10, IL17, HSP70, and HSP90 (). (b) LNT alone or combined with Oxa induced the mRNA expression levels of HMGB1, ANXA1, IFNA1, and CALR (). (c) CALR, HSP70, and HSP90 protein expression levels were increased by LNT alone or in combination with Oxa (). Each experiment was repeated three times, with the findings given as deviation. Contrast with control at . To find differences between the groups, statistical analysis using one-way analysis of variance (ANOVA) was used.

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