[Retracted] Efficacy of Glucocorticoids and Glucocorticoid-Induced Hyperglycaemia in Renal Disease: A Meta-Analysis of Randomized Controlled Trials

Table 1

Characteristics of interventions and populations at baseline and end of treatment in included RCTs.

RCTs	The primary disease	Drugs		Baseline characteristics	Follow-up months	Treatment group		Control group
		Treatment group	Control group			Sample sizes	DRF	Sample sizes	DRF
Ronald 2006	IgAN	Prednisone 60 mg/m^2 every other day for 3 months, and then 40 mg/m^2 every other day for 9 months, and then 30 mg/m^2 every other day for 12 months	Placebo	Age<40; renal biopsy showing IgAN; eGFR>50 ml/min per 1. 73m^2; UPCR≥1. 0 g/g or moderate proteinuria, UP/C ratio ≥0. 5plus renal biopsy changes	24	30	2	29	4
lv 2009	IgAN	Prednisone 0. 8 to 1. 0 mg/kg/d, for 8 weeks, then the dose was tapered by 5 to 10 mg every 2 week	Cilazapril alone	Renal biopsy showing IgAN; age18~65years; urine protein excretion of 1 to 5 g/d; eGFR≥30 mL/min	24	33	1	30	7
Fellström2017	IgAN	TRF-budesonide 16 mg/d and 8 mg/day	Placebo	Persistent proteinuria (UPCR ≥0·5 g/g or proteinuria ≥0·75 g/day); eGFR≥45 mL/min)	9	51(8 mg/d); 49(16 mg/d)	0	50	0
lv 2017	IgAN	Methylprednisolone 0. 6-0. 8 mg/kg/d, then tapered by 8 mg/d each month	Placebo	Proteinuria≥1 g/d and eGFR of 20~120 mL/min	6 ~ 8	136	8	126	20
Rauen, T. 2015	IgAN	Methylprednisolone, administered intravenously at a dose of 1 g per day for 3 days at the start of months 1, 3, and5; oral prednisolone at a dose of 0. 5 mg per kilogram per 48 hours on the other days	Supportive care	Age 18~70 year; proteinuria level above 0. 75 g/d; impaired renal function(eGFR 60-90 mL/min)	6	55	<21	80	22
Rauen, T. 2018	IgAN	Methylprednisolone, administered intravenously at a dose of 1 g per day for 3 days at the start of months 1, 3,and5; oral prednisolone at a dose of 0. 5 mg per kilogram per 48 hours on the other days	Supportive care	GFR>60 ml/min	6	55	12	54	16
Shoji 2000	IgAN	Prednisolone 0. 8 mg/kg/day and tapering to 10 mg q. o. d. 1 year	Dypiridamole 300 mg/day	Proteinuria less than 1. 5 g/day; plasma creatinine concentrations<1. 5 mg/dl. Age 15 and 55 years.	12	11	0	8	0