Construct and Validate a Predictive Model for Surgical Site Infection after Posterior Lumbar Interbody Fusion Based on Machine Learning Algorithm
Table 1
Baseline characteristics of all patients included in the study.
Total
Non-SSI
SSI
value
Number of patients
584
551 (94.35%)
33 (5.65%)
Age (years)
<0.001
Operation time
0.095
EBL
0.125
Pre WBC
0.937
Pre RBC
0.041
Pre Hb
0.229
Pre erythrocyte volume
0.179
Pre PLT
0.619
Pre neutrophil percentage
0.490
Pre lymphocyte percentage
0.795
Pre Alb
<0.001
Pre globulin
0.137
Pre ALT
0.658
Pre AST
0.342
Pre creatinine
0.208
BMI
0.456
Sex (%)
0.342
Female
321 (54.97)
306 (55.54)
15 (45.45)
Male
263 (45.03)
245 (44.46)
18 (54.55)
Diagnosis (%)
0.625
Lumbar disc herniation
284 (48.63)
269 (48.82)
15 (45.45)
Lumbar spinal stenosis
137 (23.46)
127 (23.05)
10 (30.3)
Lumbar instability/spondylolisthesis
163 (27.91)
155 (28.13)
8 (24.24)
Number of fusion segments
0.040
1-2
549 (94)
521 (94.56)
28 (84.8)
≥3
35 (6)
30 (5.44)
5 (15.2)
Allograft bone
0.081
No
554 (94.86)
525 (95.28)
29 (87.9)
Yes
30 (5.14)
26 (4.72)
4 (12.1)
Weather
0.408
Cold
315 (53.94)
300 (54.45)
15 (45.45)
Warm
269 (46.06)
251 (45.55)
18 (54.55)
Dural tear
<0.001
No
557 (95.38)
532 (96.55)
25 (75.76)
Yes
27 (4.62)
19 (3.45)
8 (24.24)
Hypertension
0.107
No
417 (71.4)
398 (72.23)
19 (57.58)
Yes
167 (28.6)
153 (27.77)
14 (42.42)
Diabetes
<0.001
No
483 (82.71)
467 (84.75)
16 (48.48)
Yes
101 (17.29)
84 (15.25)
17 (51.52)
CHD
0.073
No
555 (95.03)
526 (95.46)
29 (87.88)
Yes
29 (4.97)
25 (4.54)
4 (12.12)
RD
0.002
No
573 (98.12)
544 (98.73)
29 (87.88)
Yes
11 (1.9)
7 (1.27)
4 (12.12)
Smoking
0.174
No
454 (77.74)
432 (78.40)
22 (66.67)
Yes
130 (22.26)
119 (21.60)
11 (33.33)
Alcohol
0.613
No
471 (80.65)
446 (80.94)
25 (75.76)
Yes
113 (19.35)
105 (19.06)
8 (24.24)
Osteoporosis
0.519
No
476 (81.51)
451 (81.85)
25 (75.76)
Yes
108 (18.49)
100 (18.15)
8 (24.24)
ASA
0.010
1-2
394 (67.47)
379 (68.78)
15 (45.45)
3
190 (32.53)
172 (31.22)
18 (54.55)
NYHA
0.639
≤2
560 (95.89)
529 (96.01)
31 (93.94)
3
24 (4.11)
22 (3.99)
2 (6.06)
EBL: estimated intraoperative blood loss; Pre WBC: preoperative white blood cell count; Pre RBC: preoperative red blood cell count; Pre Hb: preoperative hemoglobin; Pre erythrocyte volume: preoperative erythrocyte volume; Pre PLT: preoperative platelets; Pre neutrophil percentage: preoperative neutrophil percentage; Pre lymphocyte percentage: preoperative lymphocyte percentage; Pre Alb: preoperative albumin; Pre globulin: preoperative globulin; Pre ALT: preoperative alanine aminotransferase; Pre AST: preoperative aspartate aminotransferase; Pre creatinine: preoperative creatinine; BMI: body mass index; CHD: coronary heart disease; ASA: American Society of Anesthesiologists; NYHA: New York Heart Association Class; SSI: surgical site infection; RD: rheumatic disease.
