Mechanism of miR-760 Reversing Lung Cancer Immune Escape by Downregulating IDO1 and Eliminating Regulatory T Cells Based on Mathematical Biology

<div>miR-760 could target IDO1. (a) The IDO1 mRNA level in cells transfected with miR-760-mimics/miR-760-inhibit is tested via qRT-PCR. (b) The IDO1 protein level in cells transfected with miR-760-mimics/miR-760-inhibit is tested via WB. (c) The IDO1 level in tumor tissues of NSCLC patients is tested via qRT-PCR. (d) The correlation between IDO1 and miR-760 in tumor tissues of NSCLC patients is assessed via Pearson test. (e) Binding and mutation sites of miR-760 and IDO1. 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Computational and Mathematical Methods in Medicine

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Figure 3

Figure 3: Mechanism of miR-760 Reversing Lung Cancer Immune Escape by Downregulating IDO1 and Eliminating Regulatory T Cells Based on Mathematical Biology 

Figure 3 | Mechanism of miR-760 Reversing Lung Cancer Immune Escape by Downregulating IDO1 and Eliminating Regulatory T Cells Based on Mathematical Biology 