Development of an Independent Prognostic Signature Based on Three Hypoxia-Related Genes for Breast Cancer

Figure 3

The construction of the prognostic model for BC. (a) The forest plot of Univariate Cox regression analysis with 26 HRGs which were significantly related to the prognosis of BC. HR: hazard ratio; 95% CI: the 95% confidence interval. (b) The tuning parameter lambda was determined by LASSO regression analysis. The optimal lambda value was obtained after taking the log below the dotted line, and the number of variables was corresponding to the top of the optimal lambda. (c) The coefficient spectrum of LASSO Cox regression model.

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