Development of an Independent Prognostic Signature Based on Three Hypoxia-Related Genes for Breast Cancer

Figure 5

Immune status of BC samples in two subgroups. (a) The relative proportion of immune infiltration in all BC samples. (b) The correlation matrix of 22 immune cell proportions. Red indicated positive correlation; blue indicated negative correlation. The darker the color, the greater the correlation. (c) The violin plot of immune cells with significantly different proportions of infiltration in the high- and low-risk groups. The horizontal axis: high- or low-risk group and the vertical axis: the relative proportion of infiltrating immune cells. value was determined by Wilcoxon test. (d) The correlative circos diagram between Risk Score and the expressions of five prominent immune checkpoints. (e) The violin plot of immune checkpoints with significantly different expressions between high- and low-risk groups.

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