Development of an Independent Prognostic Signature Based on Three Hypoxia-Related Genes for Breast Cancer

Table 1

The clinical information of samples in the two groups (training set and testing set) from TCGA database.

Characteristics	Groups	Patients samples				value
		Total ()	Training cohort ()	Testing cohort ()
		Number	Number	Number
Sex	Female	1070	533	537	1.3483	0.5096
	Male	12	8	4
Age at diagnosis	Median	58	58	58	0	1
	Range	26-90	26-89	26-90
Pathological TNM stage	I	182	90	92	1.8478	0.9974
	II	615	304	311
	III	243	123	120
	IV	20	12	8
	X	11	7	4
	Unknown	11	5	6
Vital status	Alive	928	470	458	1.0902	0.5798
	Dead	154	71	83
Radiation therapy	NO	424	222	202	2.1816	0.7024
	YES	547	269	278
	Unknown	111	50	61
Disease type	Ductal and lobular neoplasms	1039	518	521	8.3634	0.7561
	Cystic, mucinous and serous neoplasms	16	5	11
	Complex epithelial neoplasms	14	10	4
	Adenomas and adenocarcinomas	3	3	0
	Epithelial neoplasms, NOS	5	3	2
	Squamous cell neoplasms	2	1	1
	Other	3	1	2
Race	Asian	58	28	30	2.1873	0.9747
	American Indian or Alaska native	1	0	1
	Black or African American	181	91	90
	White	757	384	373
	Unknown	85	38	47