Efficacy and Safety of Treating Refractory Bone and Soft Tissue Sarcoma with Anlotinib in Different Treatment Patterns

Table 7

Treatment-related adverse events (, %).

AEs	Grades 1–2	Grades 3–4	Total
Hand-foot syndrome	12 (27)	1 (2)	13 (30)
Diarrhea	8 (18)	0 (0)	8 (18)
Hoarseness or sore throat	7 (16)	0 (0)	7 (16)
Vomit	4 (9)	0 (0)	4 (9)
Hypertension	3 (7)	1 (2)	4 (9)
Pleural effusion	0 (0)	2 (5)	2 (5)
Pneumothorax	1 (2)	2 (5)	3 (7)
Anemia	0 (0)	1 (2)	1 (2)
Hemoptysis	0 (0)	1 (2)	1 (2)