Research Article
[Retracted] Prediction of Cancer-Specific Survival of Brainstem Glioma in Children Based on Risk Stratification Model
Table 1
Patient demographics and clinicopathological characteristics of the study population.
| Factors | Entire cohort () | Training cohort () | Validation cohort () | | % | | % | | % |
| Age at diagnosis, years | | | | | | | Median | 6 | 6 | 6 | Range | 0–12 | 0–12 | 0–12 | Race | | | | | | | White | 596 | 74.0 | 426 | 75.3 | 170 | 70.8 | Black | 138 | 17.1 | 101 | 17.8 | 37 | 15.4 | Other | 72 | 8.9 | 39 | 6.9 | 33 | 13.8 | Sex | | | | | | | Male | 389 | 48.3 | 278 | 49.1 | 111 | 46.2 | Female | 417 | 51.7 | 288 | 50.9 | 129 | 53.8 | Year of diagnosis | | | | | | | 1998–2008 | 457 | 56.7 | 311 | 54.9 | 146 | 60.8 | 2009–2016 | 349 | 43.3 | 255 | 45.1 | 94 | 39.2 | Tumor size, diameter, cm | | | | | | | ≤3 | 87 | 10.8 | 54 | 9.5 | 33 | 13.8 | >3 | 265 | 32.9 | 197 | 34.8 | 68 | 28.3 | Unknown | 454 | 56.3 | 315 | 55.7 | 139 | 57.9 | Histologic grade | | | | | | | Well-differentiated | 10 | 1.24 | 8 | 1.4 | 2 | 0.8 | Moderately differentiated | 25 | 3.1 | 17 | 3 | 8 | 3.3 | Poorly differentiated | 10 | 1.24 | 7 | 1.24 | 3 | 1.3 | Undifferentiated | 22 | 2.73 | 16 | 2.8 | 6 | 2.5 | Unknown | 739 | 91.7 | 518 | 91.5 | 221 | 92.1 | Stage | | | | | | | Localized | 720 | 89.3 | 506 | 89.4 | 214 | 89.2 | Regional | 76 | 9.4 | 51 | 9.0 | 25 | 10.4 | Distant | 10 | 1.2 | 9 | 1.6 | 1 | 0.4 | Surgery | | | | | | | None | 781 | 96.9 | 551 | 97.3 | 230 | 95.8 | Yes | 25 | 3.1 | 15 | 2.7 | 10 | 4.2 | Radiotherapy | | | | | | | None | 239 | 29.6 | 169 | 29.9 | 70 | 29.2 | Yes | 567 | 70.4 | 397 | 70.1 | 170 | 70.8 | Chemotherapy | | | | | | | None | 446 | 55.3 | 310 | 54.8 | 136 | 56.7 | Yes | 360 | 44.7 | 256 | 45.2 | 104 | 43.3 | Median follow-up, months | 11 | 11 | 11 |
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