[Retracted] Prediction of Cancer-Specific Survival of Brainstem Glioma in Children Based on Risk Stratification Model

Table 2

Univariate and multivariate analyses for the training cohort.

Factors	Univariate analysis			Multivariate analysis			Score
	HR	95% CI		HR	95% CI
Age at diagnosis, years
≤6	1			1			16
>6	0.6	0.5–0.8	<0.001	0.8	0.6–1.0	0.030	0
Race
White	1			1			5
Black	0.9	1.0–1.2	0.037	0.8	1.1–1.2	0.035	3
Other	1.4	0.9–2.0	0.111	0.6	0.3–2.1	0.375	0
Sex
Male	1			1
Female	1.3	1.0–1.5	0.028	1.1	0.9–1.3	0.586
Year of diagnosis
1998–2008	1
2009–2016	0.9	0.8–1.2	0.568
Tumor size, diameter, cm
≤3	1			1			0
>3	4.6	2.8–7.6	<0.001	1.9	1.1–3.1	0.013	4
Unknown	2.8	1.7–4.5	<0.001	1.7	1.0–2.8	0.037	7
Histologic grade
Well-differentiated	1			1			0
Moderately differentiated	0.7	0.2–3.0	0.669	0.8	0.2–3.1	0.722	3
Poorly differentiated	3.4	0.9–13.2	0.075	1.5	2.1–5.8	0.021	5
Undifferentiated	4.8	1.4–16.6	0.013	2.1	0.6–7.3	0.248	8
Unknown	2.1	0.7–6.7	0.189	1.3	0.4–4.0	0.682	10
Stage
Localized	1			1
Regional	1.4	1.0–1.9	0.068	1.2	0.9–1.7	0.292
Distant	2.4	1.2–4.7	0.009	1.5	0.7–2.9	0.275
Surgery
None	1
Yes	0.6	0.3–1.2	0.164
Radiotherapy
None	1			1			0
Yes	5.9	4.3–8.2	<0.001	4.7	3.3–6.6	<0.001	100
Chemotherapy
None	1			1
Yes	1.8	1.5–2.3	<0.001	1.0	0.8–1.3	0.779

Bold text indicates significant variable (). Abbreviation: HR: hazard ratio.