[Retracted] Clinicopathological Characteristics of Nonfunctional Pancreatic Neuroendocrine Neoplasms and the Effect of Surgical Treatment on the Prognosis of Patients with Liver Metastases: A Study Based on the SEER Database
Table 4
Predictors of survival identified by multivariate Cox regression analysis in NF-pNEN patients with liver metastasis.
Variable
Number of NF-pNEN patients with liver metastasis () (%)
Survival rate (%)
value
Hazard ratio
95% CI
value
3 years
5 years
Primary site
0.124
Head
161 (30.3)
47.7
33.8
1.000
Body
46 (8.7)
50.6
44.3
0.691
0.442-1.080
0.104
Tail
211 (40.0)
57.1
46.7
0.676
0.514-0.888
0.005
Islet
3 (0.5)
0
0
1.235
0.304-5.014
0.767
Others
12 (2.3)
50.0
50.0
0.670
0.294-1.527
0.341
Overlapping
54 (10.2)
51.5
37.4
0.787
0.523-1.183
0.249
NOS
42 (8.0)
49.1
29.7
0.946
0.606-1.478
0.809
Grade
<0.001
G1
245 (46.3)
63.4
48.4
1.000
G2
140 (26.5)
63.7
51.8
0.949
0.696-1.294
0.740
G3
106 (20.0)
21.8
16.8
3.410
2.574-4.516
<0.001
G4
38 (7.2)
23.1
23.1
3.448
2.274-5.229
<0.001
Tumor size (mm)
0.333
0-20
42 (7.9)
59.1
59.1
1.000
21-40
177 (33.5)
53.8
40.0
1.390
0.850-2.275
0.190
≥40
310 (58.6)
50.5
38.8
1.424
0.886-2.288
0.144
Surgery
<0.001
Yes
212 (40.0)
77.3
66.2
1.000
No
317 (60.0)
35.4
23.1
3.645
2.773-4.79
<0.001
NOS: not otherwise specified. was considered statistically significant.