Research Article
[Retracted] Clinical Efficacy of Creatine Phosphate Sodium and/or Vitamin C in the Treatment of Children with Viral Myocarditis: A Meta-Analysis
Table 1
Basic characteristics of included literature.
| Study | Year | Intervention | No. participants (Ob/Co) | Age(years) | Gender (male/female) | Study design | Outcome measured | Observation group | Control group | Observation group | Control group |
| Baoqin Tao [10] | 2021 | Vitamin C combined with immunoglobulin | 63/45 | | | 33/30 | 24/21 | RCT | ①③④⑥ | Xiaojie Yang [11] | 2021 | Vitamin C combined with sodium creatine phosphate | 40/40 | | | 21/19 | 21/19 | RCT | ①②③⑤ | Qingyue Yu [12] | 2020 | Vitamin C combined Creatine phosphate sodium | 31/31 | | | 20/11 | 21/10 | RCT | ①②③④ | Yuantao Lin [13] | 2015 | Phosphate sodium and captopril | 40/40 | | | 21/19 | 20/20 | RCT | ①⑦ | Junying Sun [14] | 2015 | Creatine phosphate sodium and thymopeptides | 37/37 | | | — | — | RCT | ①②③ | Yuan Liu [15] | 2021 | Creatine phosphate sodium and immunoglobulin | 67/67 | | | 34/33 | 36/31 | RCT | ④⑤ | Chunli Li [16] | 2019 | Ulinastatin combined with creatine phosphate sodium | 80/75 | | | 60/20 | 56/19 | RCT | ①②③④⑤ | Jinghui Li [17] | 2021 | Gamma globulin combined with creatine phosphate | 62/59 | | | 35/27 | 34/25 | RCT | ①②③④⑤ | Ruibo Gao [18] | 2018 | Vitamin C combined immunoglobulin | 38/38 | 3-11 | 3-12 | 22/16 | 23/15 | RCT | ②③ | Huimin Yang [19] | 2021 | Sodium fructose diphosphate combined with creatine phosphate acupuncture | 42/42 | | | 24/18 | 25/17 | RCT | ①②③⑦ | Yizhen Gong [20] | 2017 | Adenosine cyclophosphate combined with vitamin C | 44/44 | 7-12 | 6-12 | 25/19 | 24/20 | RCT | ③④⑦ | Jun Liao [21] | 2016 | Adenosine cyclophosphate combined with vitamin C | 55/55 | | | 33/22 | 32/23 | RCT | ①③④⑤⑥ | Xiu Chang [22] | 2016 | Adenosine cyclophosphate combined with vitamin C | 48/48 | | | 27/21 | 26/22 | RCT | ④⑤ | Caihong Li [23] | 2016 | Astragalus granules combined with vitamin C | 68/73 | | | 36/32 | 40/33 | RCT | ②③④ | Yujia Li [24] | 2018 | Creatine phosphate sodium combined with ribavirin | 48/48 | | | 28/20 | 25/23 | RCT | ①②③④⑤ | Yue Jiang [25] | 2020 | Sodium creatine phosphate combined with vitamin C | 36/36 | | | 15/21 | 16/20 | RCT | ②③④⑥ | Quan Yuan [26] | 2016 | Sodium creatine phosphate combined with Xinjikang granules | 80/80 | | | 46/34 | 44/36 | RCT | ①②③④⑤ | Suyuan Hu [27] | 2015 | Vitamin C combined with adenosine cyclophosphate | 65/65 | — | — | 34/31 | 33/32 | RCT | ①⑥⑦ | Meng Wang [28] | 2020 | Vitamin C combined with immunoglobulin | 45/45 | | | 24/21 | 23/22 | RCT | ①⑥ |
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Note: ob: observation group; co: control group; RCT: randomized controlled trial; ①: treatment effective rate, ②: cardiac troponin-I, ③: creatine kinase isoenzyme, ④: lactate dehydrogenase, ⑤: aspartate aminotransferase, ⑥: tumor necrosis factor-α, ⑦: superoxide dismutase.
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