Exploring the Potential Mechanism of Artemisinin and Its Derivatives in the Treatment of Osteoporosis Based on Network Pharmacology and Molecular Docking

<table class="table-group" id="tab2"><tr><td><table class="table"><tr><td class="thead-hr" colspan="2"><hr/></td></tr><tr class="thead"><td class="align_left">Molecules</td><td class="align_center">Targets</td></tr><tr><td class="thead-hr" colspan="2"><hr/></td></tr><tr><td class="align_left">Common</td><td class="align_center">MAPK14</td></tr><tr><td class="align_left">ARS specific</td><td class="align_center">CASR, TTR, TGFBR1, ALPL, TRPV1, CACNA1C, PDGFRB, CCR3, CRHR1, ADRA1D, HSP90AA1, KAT2B</td></tr><tr><td class="align_left">DHA specific</td><td class="align_center">CYP3A4, MAPK3, CSF1R, VDR, CYP17A1, ASAH1, CYP11B1, CYP2D6, TOP2A, BRS3, LGMN</td></tr><tr><td class="align_left">ART specific</td><td class="align_center">NR3C1, LTB4R, DPP4, ACE, PTGER4, PPARG, PTGER2, THRB, ELANE, THRA, AGTR1, HNF4A, LPAR3, PPARA, PTPN11, PRKAA1, PRKAA2, SOAT1</td></tr><tr><td class="align_left">ARM specific</td><td class="align_center">PGR</td></tr><tr><td class="align_left">ARE specific</td><td class="align_center">PTK2B, MMP13, CTSK, SCN9A, ADAMTS4, ADRA1A, NR4A1, MTOR</td></tr><tr class="table-tr"><td colspan="2"><hr class="tbody-hr"/></td></tr></table></td></tr></table>

<div>The common targets and specific targets of five molecules against OP.</div>

Computational and Mathematical Methods in Medicine

tab2

Table 2

Table 2: Exploring the Potential Mechanism of Artemisinin and Its Derivatives in the Treatment of Osteoporosis Based on Network Pharmacology and Molecular Docking 

Table 2 | Exploring the Potential Mechanism of Artemisinin and Its Derivatives in the Treatment of Osteoporosis Based on Network Pharmacology and Molecular Docking 