Research Article
[Retracted] Long Noncoding RNA LINC00473 Ameliorates Depression-Like Behaviors in Female Mice by Acting as a Molecular Sponge to Regulate miR-497-5p/BDNF Axis
Figure 5
miR-497-5p upregulation could harbor the improving effects of LINC00473 overexpression on depression. LV-LINC00473 was coinjected with miR-497-5 mimic lentiviral vector into the hippocampal region of the CUMS-induced female mice. (a) Sucrose preference in SPT. (b) Immobility time of mice in TST. (c) Cold water immobility time of mice in FST. (d) Open arm time in EPM. (e) ELISA was used to detect the concentration of the hypothalamic neurotransmitters. ; and .
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