Research Article

[Retracted] Long Noncoding RNA LINC00473 Ameliorates Depression-Like Behaviors in Female Mice by Acting as a Molecular Sponge to Regulate miR-497-5p/BDNF Axis

Figure 7

BDNF knockdown abolished the impacts of miR-497-5p inhibitor on depression. The hippocampal region of CUMS-induced depressed female mice was injected with miR-497-5p inhibitor alone or coinjected with miR-497-5p inhibitor and sh-BDNF lentiviral vector together. (a and b) The protein expression of BDNF in the hippocampus was tested by western blot. (c–f) Behavioral testing was carried out via evaluating sucrose preference in SPT, immobility time in TST, cold water immobility time in FST, and time in open arm in EPM. (g) The hypothalamic neurotransmitter concentration determination. ; and .
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