In Silico Analysis Identifies Upregulated lncRNA DLGAP1-AS1 Which Is Correlated to Poor Prognosis and Promotes Cell Proliferation in Glioblastoma

Figure 4

DLGAP1-AS1 was upregulated in GBM. (a) CGGA database analysis showed that DLGAP1-AS1 was differently expressed in WHO II, WHO III, and WHO IV gliomas. (b) CGGA database analysis showed that DLGAP1-AS1 was higher in IDH1 wildtype glioma than in IDH1-mutant glioma samples. (c) CGGA database analysis showed that DLGAP1-AS1 was higher in IDH1 wildtype tumor than in IDH1-mutant tumor samples in WHO II, WHO III, and WHO IV patients. (d) CGGA database analysis showed that DLGAP1-AS1 was higher in 1p/19q noncodeletion glioma than in 1p/19q codeletion glioma samples. (e) CGGA database analysis showed that DLGAP1-AS1 was dysregulated in 1p/19q noncodeletion samples highly expressed DLGAP1-AS1 in WHO II, WHO III, and WHO IV patients. (f) CGGA database analysis showed that DLGAP1-AS1 was higher in glioma patients older than 42 than glioma samples younger than 42 years old. (g) TCGA database analysis showed that GBM and LGG tissues highly expressed DLGAP1-AS1 compared to normal tissues.

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