Integrative Bioinformatics Analysis Reveals That miR-524-5p/MEF2C Regulates Bone Metastasis in Prostate Cancer and Breast Cancer

Figure 5

miR-524-5p specifically targets MEF2C. (a) The expression of MEF2C in DU145 or MCF7 cells after transfection with miR-524-5p mimics. (b) The protein expression of MEF2C in DU145 or MCF7 cells after transfection with miR-524-5p mimics. (c) Schematic representation of the predicted target site for miR-524-5p in MEF2C. (d) Luciferase activity assay in the wild-type or mutant reporter containing MEF2C 3 UTR (two sites) when transfected with miR-524-5p mimics or NC in 293 T cells.

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