Research Article
Detection of the Content of Two Coumarins, IM and ISOIM, and Their Mechanism of Action on Colitis Rats in Angelica albicans
Table 4
Extraction recovery, matrix impacts, and stability of IM and ISOIM in rat plasma.
| Constituents | Conc. nominal (ng/mL) | Recovery rate in % | Matrix (%) | Durability (%) |
| | | | | Free-thaw cycles | At -70 °C for 30 days | At room for 24 hrs | IM | 2 | 84.9 | 91 | 97 | 99 | 97 | 50 | 83.4 | 92 | 100 | 101 | 100 | 150 | 79.8 | 85 | 101 | 94 | 101 | ISOIM | 2 | 85.3 | 94 | 101 | 98 | 95 | 50 | 75.6 | 96 | 98 | 98 | 100 | 150 | 70.3 | 94 | 95 | 97 | 97 |
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