[Retracted] GEO Database Screening Combined with In Vitro Experiments to Study the Mechanism of hsa_circ_0003570 in Infantile Hemangiomas

Figure 4

The effect of hsa_circ_0003570 on the malignant biological behavior of HEMEC cells could be reversed by hsa-miR-138-5p. (a) The expression levels of hsa_circ_0003570 and hsa-miR-138-5p in HEMEC transfected with no transfection group (control), no temple control (si-NC), si-hsa_circ_0003570, si-hsa_circ_0003570+hsa-miR-138-5p inhibitor, and hsa-miR-138-5p mimic were detected by quantitative real-time polymerase chain reaction (qRT-PCR). (b) The cell proliferation ability of HEMEC transfected with control, si-NC, si-hsa_circ_0003570, si-hsa_circ_0003570+hsa-miR-138-5p inhibitor, and hsa-miR-138-5p mimic was detected by MTT. (c) and (d) Cell migration and invasion ability of HEMEC transfected with control, si-NC, si-hsa_circ_0003570, si-hsa_circ_0003570+hsa-miR-138-5p inhibitor, and hsa-miR-138-5p mimic was detected by Transwell assay. (e) The apoptosis rate of HEMEC transfected with control, si-NC, si-hsa_circ_0003570, si-hsa_circ_0003570+hsa-miR-138-5p inhibitor, and hsa-miR-138-5p mimic was detected by flow cytometry. , , compared with Control.

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