Research Article

[Retracted] Functional Analysis of Bronchopulmonary Dysplasia-Related Neuropeptides in Preterm Infants and miRNA-Based Diagnostic Model Construction

Figure 5

Expression of neuropeptides in the ceRNA network and their ability to classify BPD. (a) Sankey diagram demonstrating three miRNA-NP mRNA regulatory pairs in the ceRNA network; (b) differential expression of the neuropeptide-related genes OPRL1 and NPPA between samples from the BPD and control groups; (c) the AUC values of the diagnostic classification ability of OPRL1 and NPPA for BPD were shown; (d) gene set enrichment analysis (GSEA) of OPRL1 indicates the KEGG CYTOKINE CYTOKINE RECEPTOR INTERACTION pathway and NABA ECM REGULATORS pathway are elevated. (e) GSEA of NPPA indicated the KEGG NEUROACTIVE LIGAND RECEPTOR INTERACTION pathway and the REACTOME ADORA2B MEDIATED ANTI INFLAMMATORY pathway.
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