Effect of Hypertonic Saline Solution Combined with Furosemide on Acute Heart Failure: A Meta-Analysis

Table 1

Basic characteristics of literature and risk assessment of bias.

Author	Year	No. of patients		Outcomes	Risk of basis
		HSS+ furosemide	Furosemide
Issa et al. [21]	2013	20	12	Urine output, length of stay, readmission rate, hospitalization cost, mortality, readmission time	Uncertain
Licata et al. [19]	2003	53	54	Urine output, serum creatinine, readmission rate, mortality, body weight	Uncertain
Okuhara et al. [22]	2014	22	22	Urine output, brain natriuretic peptide, natriuretic capacity, length of hospital stay, readmission rate, mortality	Low
Parrinello et al. [23]	2012	66	67	Length of hospital stay, readmission, and mortality	Uncertain
Parrinello et al. [24]	2011	122	126	Urine volume, serum creatinine, readmission rate, length of hospital stay, natriuretic capacity, body weight, mortality	Uncertain
Paterna et al. [25]	2005	30	30	Brain natriuretic peptide, body weight, urine volume, serum creatinine	Uncertain
Paterna et al. [26]	2011	48	46	Serum creatinine, body weight, length of stay, readmission rate	Uncertain
Paterna et al. [27]	2000	881	890	Urine volume, serum creatinine, body weight, readmission rate, mortality	Uncertain
Wan et al. [28]	2017	132	132	Urine volume, serum creatinine, body weight, brain natriuretic peptide	Uncertain
Yayla et al. [20]	2015	14	14	Urine volume, serum creatinine, body weight	Low

Note: HSS: hypertonic saline solution.