[Retracted] Association between the Platelet-Derived Growth Factor/Platelet-Derived Growth Factor Receptor System and Risk of Rheumatoid Arthritis: A Systematic Review and Meta-Analysis
Table 1
Characteristics of respective studies included in the meta-analysis.
Author
Year
Country
Rheumatoid arthritis (RA)
Control/nonarthritis (NA)
Cohort
Sample
Detection
Gene
PDGF/PDGFR expression (RA)
PDGF/PDGFR expression (NA)
Rubin
1988
Sweden
15
5
20
STB
IHC
PDGFR
15
0
Watanabe
2002
Japan
3
3
6
STB
RT-PCR
PDGFRA
2
1
Walsh
2010
UK
10
11
21
CSMTMTP
IHC
PDGFB
10
0
Charbonneau (pdgfA)
2016
Canada
6
4
10
STB
IHC
PDGFA
2
2
Charbonneau (pdgfB)
2016
Canada
6
4
10
STB
IHC
PDGFB
4
1
Charbonneau (pdgfC)
2016
Canada
6
4
10
STB
IHC
PDGFC
4
1
Charbonneau (pdgfD)
2016
Canada
6
4
10
STB
IHC
PDGFD
4
2
Matsumura
2019
Japan
25
13
38
STB
IHC
PDGFRA/B
15
5
Wang
2020
China
49
49
98
VWB
ELISA
PDGFB
34
15
VWB: venous whole blood; STB: synovial tissue biopsy; CSMTMTP: coronal section of middle third of medial tibial plateaux; ELISA: enzyme-linked immunosorbent assay; IHC: immunohistochemistry; RT-PCR: real-time polymerase chain reaction.