Research Article

[Retracted] Dapagliflozin Inhibits Ventricular Remodeling in Heart Failure Rats by Activating Autophagy through AMPK/mTOR Pathway

Figure 1

DAPA attenuated left VR and improved cardiac function in HF rats. (a) HE staining assessed histopathological changes in left ventricular myocardial tissue of rats in control, model, or DAPA group. (b), Quantitative analysis of cardiomyocyte diameter in left ventricular tissue of rats in each group. (c)–(f) Quantitative analysis of HW, LVW, HW/TL ,and LVW/TL of rats in each group. (g, h) ELISA measured plasma ANP and BNP levels of rats in each group. (i) M-mode echocardiography detected cardiac function of rats in each group. (j)–(m) Quantitative analysis of LVIDs, LVIDd, EF, and FS of rats in each group. , ; #, ##.
(a)
(b)
(c)
(d)
(e)
(f)
(g)
(h)
(i)
(j)
(k)
(l)
(m)