Research Article

Clinical Efficacy, Survival, and Adverse Reaction Evaluation of Immune Checkpoint Inhibitor in Advanced Gastric Cancer: A Systematic Review and Meta-Analysis

Table 1

Basic characteristics of literature.

Include the literatureYear of publication (C/T)Intervention methodOutcome indexCourse of treatmentWhether it is random or notWhether it is blind or not
CT

Zheng Guili [17]202140/40FOLFOX4Chemotherapy regimenFOLFOX4Chemotherapy regimen+PD-1Inhibitor①②③6 courses of treatmentYesNo
Liang Lijun [18]202243/43Irinotecan/paclitaxel + tigio + apatinib mesylateIrinotecan/paclitaxel + tigio + apatinib mesylate + Carrell monoclonal antibody①④⑤24 weeksYesNo
Shen Wang [19]202245/43AlotinibAlotinib + Carrilizu monoclonal antibody①②⑤4 courses of treatmentYesNo
Zhang Lianhua [20]202140/40Docetaxel + irinotecan hydrochloride + tigioDocetaxel + irinotecan hydrochloride + tigio + Carrell monoclonal antibody①③⑤3 cyclesNoNo
Tu Huiyang [21]202138/38XELOX/FOLFOX chemotherapy regimenXELOX/FOLFOX chemotherapy regimen + pablizumab①②③3 cyclesYesNo
Wang Junsong [22]202240/42Oxaliplatin + capecitabineOxaliplatin + capecitabine + Pabolizhu monoclonal antibody①④⑤To the progress of the diseaseYesNo

Note: C: control group; T: study group; ①: clinical efficacy; ②: immune function index; ③: tumor marker level; ④: survival time; ⑤: adverse reactions.