Diagnostic Value and High-Risk Factors of Two-Dimensional Ultrasonography Combined with Four-Dimensional Ultrasonography in Prenatal Ultrasound Screening of Fetal Congenital Malformations

Table 4

Univariate analysis of risk factors for fetal malformation.

Risk factors	Normal fetal group ()	Malformed fetus group ()
Age			22.7510	0.0069
<35	1651 (76.44)	47 (54.02)
≥35	509 (23.56)	40 (45.98)
Adverse pregnancy and childbirth history			29.3710	<0.0001
With	590 (27.31)	44 (50.57)
None	1570 (72.69)	43 (49.43)
Folic acid supplementation			7.9151	0.0049
Yes	705 (32.64)	41 (47.13)
No	1455 (67.36)	46 (52.87)
History of cold during pregnancy			1.9131	0.1666
Yes	882 (40.83)	42 (48.28)
No	1278 (59.17)	45 (51.72)
History of medication during pregnancy			54.9810	<0.0001
Yes	367 (16.99)	42 (48.28)
No	1793 (83.01)	45 (51.72)
History of toxic exposure during pregnancy			93.7010	<0.0001
Yes	77 (3.56)	22 (25.29)
No	2083 (96.44)	65 (74.71)
History			79.8510	<0.0001
Yes	74 (3.43)	20 (22.99)
No	2086 (96.57)	67 (77.01)