Research Article
[Retracted] Apatinib Functioned as Tumor Suppressor of Synovial Sarcoma through Regulating miR-34a-5p/HOXA13 Axis
Figure 2
Apatinib suppressed the SW982 cells by upregulating miR-34a-5p. The SW982 cells were stimulated with apatinib alone, apatinib along with the NC inhibitor, or apatinib and the miR-34a-5p inhibitor. (a) The expression of miR-34a-5p was determined by qPCR. (b, c) The proliferation of the cells was determined by CCK-8 and clone assays. (d) The apoptosis of the cells was evaluated by flow cytometry. (e) The migration of the cells was determined by wound healing. (f) The invasion of the cells was determined by the Transwell assay. (g) The protein levels of VEGFR2, Ki67, cleaved caspase-3, and cleaved caspase-9 in the SW982 cells were estimated by the western blot assay; , , and .
(a) |
(b) |
(c) |
(d) |
(e) |
(f) |
(g) |