Research Article

[Retracted] Efficacy and Risk Factors of Pyrrotinib in Second- and Third-Line Treatments for HER2-Positive Advanced Breast Cancer

Table 1

Baseline data of breast cancer patients with HER2-positive.

ItemsSecond-line ()Third-line ()Total ()

Age (years)
ECOG score [ (%)]
 0~116 (72.73)9 (69.23)25 (71.43)
 26 (27.27)4 (30.77)10 (28.57)
WHO grade [ (%)]
 II15 (68.18)7 (53.85)22 (62.86)
 III7 (31.82)6 (46.15)13 (37.14)
ER [positive, (%)]11 (50.00)6 (46.15)17 (48.57)
PR [positive, (%)]13 (59.09)7 (53.85)20 (57.14)
P53/P63 [positive, (%)]9 (40.91)4 (30.77)13 (37.14)
Pathological type [ (%)]
 Invasive carcinoma11 (50.00)6 (46.15)17 (48.57)
 Invasive ductal carcinoma6 (27.27)3 (23.08)9 (25.71)
 Other5 (22.73)4 (30.77)9 (25.71)
Family history [yes, (%)]1 (4.55)1 (7.69)2 (5.71)
Complications [yes, (%)]5 (22.73)2 (15.38)7 (20.00)
Surgery [yes, (%)]15 (68.18)10 (76.92)25 (71.43)
Vascular tumor thrombus [positive, (%)]8 (36.36)2 (15.38)10 (28.57)
Combination chemotherapy [ (%)]
 Capecitabine10 (45.45)4 (30.77)14 (40.00)
 Albumin paclitaxel6 (27.27)2 (15.38)8 (22.86)
 Gemcitabine2 (9.09)2 (15.38)4 (11.43)
 Other4 (18.18)5 (38.46)9 (25.71)