MiR-96-5p Facilitates Lung Adenocarcinoma Cell Phenotypes by Inhibiting FHL1

Figure 3

MiR-96-5p downregulates FHL1 expression in LUAD cells. (a) Volcano map of differential miRNAs in normal and tumor groups in TCGA database. Red indicates differentially upregulated miRNAs, and green indicates differentially downregulated miRNAs; (b) Venn diagram of predicted upstream miRNAs of FHL1 and differential miRNAs; (c) Pearson correlation analysis of FHL1 and its predicted upstream miRNAs; (d) violin plot of miR-96-5p expression in normal (green; ) and tumor (orange; ) tissue; (e) MiR-96-5p level in BEAS-2B and A549, H1650, H441, and H1299 cell lines; (f) diagram of binding of miR-96-5p and FHL1-WT and FHL1-MUT sequences; (g) luciferase activity of A549 cells in treatment groups (miR-NC and miR-mimic); (h) FHL1 mRNA level in A549 cells; (i) FHL1 protein expression in A549 cells; .

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