GPC1 Is Associated with Poor Prognosis and Treg Infiltration in Colon Adenocarcinoma

Figure 6

Validation using clinical specimens: (a) representative images of IHC staining of GPC1 in COAD and paired adjacent normal tissues; (b) IHC score of GPC1 of COAD compared with corresponding adjacent normal tissues; (c–f) associations between GPC1 IHC score and T stage ((c) ), N stage ((d) ), pathologic stage ((e) Stage I & , Stage III & ), and pathologic grade ((f) ); (g) representative images of IHC staining of GPC1 and Foxp3 in COAD; (h) number of Foxp3+ cells per high power field (HP) in GPC1 high- versus low-expressing groups; (i) associations between GPC1 IHC score and number of Foxp3+ cells per HP. Black scale  μm. Red arrow points to Foxp3+ cells.

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