Elucidation of the Key Therapeutic Targets and Potential Mechanisms of Marmesine against Knee Osteoarthritis via Network Pharmacological Analysis and Molecular Docking

<div>Identification of DEGs in OA patients. (a) PCA for GSE98918 dataset. (b) Volcano diagram of DEGs in GSE98918 dataset. The blue dots represent the downregulated genes, and the red dots represent the upregulated genes. (c) Heat map of the top 20 genes with the most significant downregulation and upregulation in GSE98918 dataset. The purple group is the OA group, while the dark green group is the control group. The downregulated genes are exhibited in blue, and upregulated genes are showed in red.</div>

Computational and Mathematical Methods in Medicine

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Figure 1: Elucidation of the Key Therapeutic Targets and Potential Mechanisms of Marmesine against Knee Osteoarthritis via Network Pharmacological Analysis and Molecular Docking 

Figure 1 | Elucidation of the Key Therapeutic Targets and Potential Mechanisms of Marmesine against Knee Osteoarthritis via Network Pharmacological Analysis and Molecular Docking 