Elucidation of the Key Therapeutic Targets and Potential Mechanisms of Marmesine against Knee Osteoarthritis via Network Pharmacological Analysis and Molecular Docking

<table class="table-group" id="tab1"><tr><td><table class="table"><tr><td class="thead-hr" colspan="4"><hr/></td></tr><tr class="thead"><td class="align_left">Target</td><td class="align_center">Degree</td><td class="align_center">Betweenness</td><td class="align_center">Closeness</td></tr><tr><td class="thead-hr" colspan="4"><hr/></td></tr><tr><td class="align_left">EGFR</td><td class="align_center">23</td><td class="align_center">585.6396</td><td class="align_center">0.276243</td></tr><tr><td class="align_left">CASP3</td><td class="align_center">20</td><td class="align_center">446.55685</td><td class="align_center">0.276243</td></tr><tr><td class="align_left">MMP9</td><td class="align_center">18</td><td class="align_center">226.11505</td><td class="align_center">0.265957</td></tr><tr><td class="align_left">PPARG</td><td class="align_center">17</td><td class="align_center">294.71487</td><td class="align_center">0.263158</td></tr><tr><td class="align_left">MAPK1</td><td class="align_center">15</td><td class="align_center">159.40509</td><td class="align_center">0.261780</td></tr><tr class="table-tr"><td colspan="4"><hr class="tbody-hr"/></td></tr></table></td></tr></table>

<div>Topological analysis of PPI network.</div>

Computational and Mathematical Methods in Medicine

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Table 1

Table 1: Elucidation of the Key Therapeutic Targets and Potential Mechanisms of Marmesine against Knee Osteoarthritis via Network Pharmacological Analysis and Molecular Docking 

Table 1 | Elucidation of the Key Therapeutic Targets and Potential Mechanisms of Marmesine against Knee Osteoarthritis via Network Pharmacological Analysis and Molecular Docking 