Research Article

An Untargeted Lipidomics Study of Acute Ischemic Stroke with Hyperglycemia Based on Ultrahigh-Performance Liquid Chromatography-Mass Spectrometry

Table 2

Differences of lipid metabolites between groups.

NumberStandard vs. normalStandard vs. managementManagement vs. normal

1Acar(20:1)CE(18:1)AcylGlcADG(22:1/22:1/14:0)
2DAG(16:0/18:0)CE(18:2)CE (18:2)
3DGTS(19:0/26:2)CE(18:3)CE (18:3)
4DGTS(2:0/17:1)CE(20:5)DGTS(2:0/17:1)
5DGTS(2:0/21:2)CE(22:4)DGTS(2:0/21:2)
6DGTS(27:0/18:1)Cer/NDS(d18:0/24:0)DGTS(27:0/18:1)
7HexCer/NS(d18:1/16:1)Cer/NS(d18:1/24:2)HexCer/NS(d18:1/16:1)
8LPC(14:0)HexCer/NS(d20:3/36:1)LPC(14:0)
9LPC(15:1)LPC(20:4)LPC(15:1)
10LPC(18:1)PC(14:0e/20:4)LPC(18:1)
11LPC(18:3)PC(14:0e/21:0)LPC(18:3)
12LPC(19:0)PC(14:0e/23:0)LPC(19:0)
13LPC(19:1)PC(14:0e/24:0)LPC(19:1)
14LPC(20:0)PC(16:1e/22:6)LPC(20:0)
15LPC(20:1)PC(18:0e/22:3)LPC(20:1)
16LPC(20:5)PC(19:1/20:4)LPC(20:2)
17LPC(24:1)PC(20:3/20:3)LPC(20:3)
18LPE(16:0)SM(d14:0/24:0)LPC(20:4)
19LPE(18:2)SM(d14:0/26:0)PC(14:0e/20:4)
20LPE(20:4)SM(d14:0/27:0)PC(14:0e/4:0)
21LPE(22:5)SM(d14:0/30:1)PC(14:1e/4:0)
22PC(11:0/22:2)TAG(12:1/19:1/19:1)PC(14:1e/6:0)
23PC(11:0/26:2)TAG(13:0/13:0/21:4)PC(16:1e/22:6)
24PC(12:0/26:1)TAG(13:0/13:0/21:5)PC(18:2/18:2)
25PC(14:0/22:5)TAG(13:0/18:2/18:2)PC(18:3/18:3)
26PC(14:0e/20:4)TAG(13:0/21:2/21:2)PC(20:4/20:4)
27PC(14:0e/22:3)TAG(13:1/18:4/18:4)PC(24:4/18:5)
28PC(14:0e/4:0)TAG(13:1/21:1/21:1)PC(3:0/18:4)
29PC(14:1e/4:0)TAG(14:0/18:2/20:5)SHexCer(d18:1/16:0)
30PC(14:1e/6:0)TAG(14:1/14:1/22:3)TAG(12:0/22:0/22:0)
31PC(16:2/22:6)TAG(15:1/19:0/21:2)TAG(12:1/12:1/19:5)
32PC(18:2/18:2)TAG(16:0/16:2/22:6)TAG(12:1/22:0/22:0)
33PC(18:3/18:3)TAG(16:0/20:4/20:4)TAG(13:0/13:0/16:0)
34PC(20:1/20:1)TAG(16:1/16:1/22:5)TAG(13:1/21:1/21:1)
35PC(21:2/21:2)TAG(16:1/18:3/20:4)TAG(16:0/18:1/22:0)
36PC(22:6/22:6)TAG(16:2/18:2/18:2)TAG(16:0/20:0/20:0)
37PC(24:4/18:5)TAG(17:0/18:5/22:0)TAG(16:0/22:1/22:1)
38SHexCer(d18:1/16:0)TAG(17:1/19:1/19:1)TAG(18:0/18:0/20:0)
39TAG(12:0/12:0/22:7)TAG(18:0/20:4/22:6)TAG(18:0/18:0/20:1)
40TAG(12:0/14:0/20:2)TAG(18:1/18:2/20:4)TAG(18:0/18:0/22:0)
41TAG(12:0/16:0/18:1)TAG(18:1/18:2/22:4)TAG(18:0/18:0/22:1)
42TAG(12:0/22:0/22:0)TAG(18:1/20:4/22:5)TAG(18:0/18:1/22:1)
43TAG(12:1/22:0/22:0)TAG(18:1/20:4/22:6)TAG(18:1/18:1/22:0)
44TAG(12:2/17:0/17:0)TAG(18:2/18:2/20:2)TAG(18:1/18:1/22:1)
45TAG(13:0/13:0/16:0)TAG(18:2/18:2/20:4)TAG(18:1/20:0/20:0)
46TAG(13:1/20:0/20:0)TAG(18:2/18:2/20:5)TAG(18:1/21:0/21:0)
47TAG(14:0/14:1/22:5)TAG(18:2/18:2/22:6)TAG(18:1/22:1/22:1)
48TAG(14:0/16:0/16:0)TAG(18:2/18:3/20:5)TAG(18:2/18:2/22:0)
49TAG(14:0/16:0/18:1)TAG(18:2/18:3/22:6)TAG(20:1/20:1/22:0)
50TAG(16:0/16:0/16:0)TAG(18:3/18:3/22:5)
51TAG(16:0/16:0/17:0)
52TAG(16:0/16:0/18:0)
53TAG(16:0/17:0/18:1)
54TAG(16:0/18:0/18:0)
55TAG(16:0/18:0/18:1)
56TAG(16:0/18:0/22:1)
57TAG(16:0/18:1/22:0)
58TAG(16:0/20:0/20:0)
59TAG(16:0/22:1/22:1)
60TAG(16:1/16:2/20:4)
61TAG(16:2/16:2/16:2)
62TAG(17:0/17:0/19:0)
63TAG(17:0/17:2/19:0)
64TAG(17:0/18:0/18:0)
65TAG(17:2/17:2/18:3)
66TAG(18:0/18:0/18:0)
67TAG(18:0/18:0/20:0)
68TAG(18:0/18:0/20:1)
69TAG(18:0/18:0/22:0)
70TAG(18:0/18:0/22:1)
71TAG(18:0/18:1/20:3)
72TAG(18:0/18:1/21:0)
73TAG(18:0/18:1/22:1)
74TAG(18:1/18:1/20:0)
75TAG(18:1/18:1/22:0)
76TAG(18:1/18:1/22:1)
77TAG(18:1/20:0/20:0)
78TAG(18:1/21:0/21:0)
79TAG(18:1/22:1/22:1)
80TAG(18:2/18:2/22:0)
81TAG(19:0/19:0/19:4)
82TAG(20:1/20:1/20:1)
83TAG(20:1/20:1/22:0)

Notes: the number of carbon chains that make up the lipid and the structure of each carbon chain is indicated in parentheses. DGTS (19:0/26:2) indicates that the diacylglyceryl trimethylhomoserine contains two carbon chains, one of which consists of 19 carbon atoms without double bonds, and the other chain consists of 26 carbon atoms containing two double bonds. PC(14:0e/20:4), e represents an ether bond in the chain structure. HexCer/NS(d18:1/16:1), d represents 2 hydroxyl groups in the chain structure. Abbreviations: Acar: acylcarnitine; AcylGlcADG: acylglucuronosyldiacylglycerol; CE: cholesteryl ester; Cer/NDS: ceramide nonhydroxy fatty acid-dihydrosphingosine; Cer/NS: ceramide nonhydroxy fatty acid-sphingosine; DAG: diacylglycerol; DGTS: diacylglyceryl trimethylhomoserine; HexCer/NS: nonhydroxy fatty acid-sphingosine; LPC: lysophosphatidylcholine; LPE: lysophosphatidylethanolamine; PC: phosphatidylcholine; SM: sphingomyelin; SHexCer: sulfur hexosylceramide hydroxy fatty acid; TAG: triacylglycerol.