A ceRNA Network Composed of Survival-Related lncRNAs, miRNAs, and mRNAs in Clear Cell Renal Carcinoma

Table 2

Univariate and multivariate Cox regression analysis of overall survival.

Overall survival	Univariate Cox analysis			Multivariate Cox analysis
	HR	95% CI	value	HR	95% CI	value
Age (<46/≥ 46)	2.263268094	1.1553-4.4337	0.017273078
Gender (male/female)	1.057248789	0.7681-1.4552	0.732716575
Race (white/nonwhite)	0.734643916	0.3868-1.3952	0.346052689
Tumor stage (I-II/III-IV)	4.156665354	2.9807-5.7965	4.57-17
lncRNA cohort				3.033	2.139-4.300	4.70-10
miRNA cohort				3.525	2.496-4.978	8.41-13
mRNA cohort				3.49	2.470-4.931	1.39-12
lncRNA signature (low risk group/high risk group)	3.985610434	2.7434-5.7903	4.00-13	2.74	1.857-4.043	3.85-07
miRNA signature (low risk group/high risk group)	2.006770711	1.4465-2.784	3.05-05	1.571	1.126-2.194	0.00793
mRNA signature (low risk group/high risk group)	2.775537016	1.9666-3.9171	6.34-09	1.595	1.141-2.228	0.00626