Research Article

[Retracted] Identification of Key Genes Related to the Obesity Patients with Osteoarthritis Based on Weighted Gene Coexpression Network Analysis (WGCNA)

Figure 5

The IPA results obtained by IPA 01-19-02 in the GSE117999 dataset. (a) DEGs were mainly associated with the antimicrobial response, inflammatory response, and humoral immune response pathways. (b) Inflammatory response, chemotaxis, cell death of leukemia cell lines, and lymphocyte migration pathways were activated, while the inflammation of organ, extracranial solid tumor, and recruitment of granulocyte pathways were inhibited. (c, d) The upstream and downstream regulatory networks displayed that the hub genes were involved in the regulation of the enzyme (c), kinase, and ligand-dependent nuclear receptor (d).
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