A Rule-Based Inference Framework to Explore and Explain the Biological Related Mechanisms of Potential Drug-Drug Interactions

Algorithm 1

If

<one drug inhibits metabolism or transport of another >

AND<one drug induces metabolism or transport of another >

AND<two drugs share the same pharmacological target >

OR<two drugs share biomolecular features>

OR<two drugs share physiological pathways >

OR<two drugs have common genetic variations >

Then

< a DDI occurs >