Research Article
[Retracted] MiR-579 Inhibits Lung Adenocarcinoma Cell Proliferation and Metastasis via Binding to CRABP2
Figure 3
CRABP2 was regulate by miR-579 (a) Through TargetScan, we found that CRABP2 is a direct target gene of miR-579. The miR-579 binding sequences on CRABP2 mRNA were mutated from 5-…AACCGCG…-3 to 5-…UUGGCGC…-3. (b) Co-expression of miR-579 mimic and wild-type CRABP2 3UTR could reduce luciferase activity, and it had no change in Calu-3 cells that co-transfected miR-579 mimic and CRABP2 MUT 3UTR. (c) CRABP2 was overexpressed in H1650, A549, and cells verse BEAS-2B. (d) The expression of CRABP2 was calculated after exogenous change miR-579. (e) CRABP2 expression was increased by inhibiting miR-579 in Calu-3 cells.
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