Research Article

[Retracted] DNMT1-Mediated DNA Methylation Targets CDKN2B to Promote the Repair of Retinal Ganglion Cells in Streptozotocin-Induced Mongolian Gerbils during Diabetic Retinopathy

Figure 4

DNA hypermethylation suppressed CDKN2B expression during diabetic retinopathy. (a) Quantitative analysis of CDKN2B mRNA expression in the control and STZ groups. (b) Western blot analysis was used to assess the protein levels of CDKN2B in the control and STZ groups. (c) Western blot analysis indicated the significantly decreased CDKN2B protein expression in the STZ group. (d) The position of the CpG sites at the upstream regulatory genomic locus of CDKN2B. Analysis of DNA methylation status at the upstream regulatory locus of the CDKN2B gene in control and WH groups determined by BSP. TSS: transcriptional start site. , .
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