Construction of Glycolytic Regulator Gene Signature to Predict the Prognosis and Tumor Immune Cell Infiltration Levels for Prostate Cancer

Figure 7

Bioinformatics analysis of glycolytic regulators in PCa. (a) The positively-related glycolytic regulators took part in regulating MAPK cascade, mitochondrial electron transport, NIK/NF-kappaB signaling, cell adhesion, mitochondrial respiratory chain complex I assembly, extracellular matrix organization, Wnt signaling pathway, mitochondrial translational elongation, inflammatory response, and angiogenesis. (b) Glycolytic regulators negatively related were involved in regulating transcription, histone acetylation, cellular response to DNA damage stimulus, covalent chromatin modification, viral process, histone H3-K4 methylation, chromatin remodeling, protein sumoylation, protein polyubiquitination, and DNA repair.

(a)

(b)