Screening of Medications for Idiopathic Membranous Nephropathy Using Glomerular Whole-Genome Sequencing

Table 1

The 10 most negatively correlated small molecule compounds screened from the CMap database.

Rank	CMap name	Dose	Cell line	Mean CMap score	value	Specificity
9	Naringin	7 μM	PC3	-0.832	0.0298	0.0777
23	Mexiletine	19 μM	PC3	-0.782	0.03681	0.0235
34	Prestwick-1080	15 μM	MCF7	-0.765	0.00147	0
36	PHA-00851261E	10 μM	PC3	-0.761	0.01169	0.0412
50	Pyrantel	11 μM	HL60	-0.739	0.02017	0.0324
52	Pyrimethamine	16 μM	PC3	-0.738	0.01232	0.0467
80	Retrorsine	11 μM	PC3	-0.715	0.03728	0.0769
85	Mecamylamine	20 μM	MCF7	-0.708	0.00096	0
91	Bisoprolol	9 μM	HL60	-0.703	0.02037	0.0055
101	PHA-00851261E	1 μM	MCF7	-0.694	0.01169	0.0412