Construction of a Colorectal Cancer Prognostic Risk Model and Screening of Prognostic Risk Genes Using Machine-Learning Algorithms

Table 1

Results of univariate COX regression.

Genes	HR	HR.95L	HR.95H	value
CALB2	1.075168531	1.046511034	1.104610780	0.000000145
MMRN1	1.177992963	1.102176923	1.259024202	0.000001390
SCG2	1.136294207	1.075992885	1.199974964	0.000004380
CHGA	1.008260884	1.004368250	1.012168604	0.000030700
CADM3	1.471082666	1.193637511	1.813016254	0.000294669
FABP4	1.010864845	1.004320872	1.017451457	0.001109783
GPX3	1.013547500	1.005364841	1.021796757	0.001139274
CLU	1.013894313	1.005458670	1.022400730	0.001207801
RCAN2	1.162898316	1.060003479	1.275781183	0.001409139
PLK1	0.951773127	0.921575359	0.982960402	0.002658353
CCND1	1.010820410	1.003524380	1.018169485	0.003593027
MGP	1.005838658	1.001872497	1.009820521	0.003877044
SGCE	1.110563713	1.030969237	1.196303166	0.005713800
MFAP4	1.009969066	1.002762350	1.017227575	0.006628391
PRELP	1.034675030	1.008960246	1.061045192	0.007938749
MAD2L1	0.933275152	0.885218560	0.983940631	0.010461483
SFRP2	1.002566577	1.000574717	1.004562402	0.011530280
AGMAT	0.968625747	0.944791385	0.993061380	0.012151343
MIPEP	0.953418072	0.916549114	0.991770115	0.017756291
VSIG4	1.033985345	1.005547554	1.063227381	0.018835922
CCDC80	1.039974343	1.006339207	1.074733675	0.019455563
FHL1	1.029753094	1.004243700	1.055910468	0.021972453
DSN1	0.958530124	0.924293285	0.994035133	0.022468282
EPB41L3	1.135963669	1.016666636	1.269259178	0.024325247
AXIN2	0.989527226	0.980342126	0.998798384	0.026921215
HEXIM1	1.041947453	1.004470807	1.080822346	0.027903087
PARM1	0.988914084	0.978997996	0.998930610	0.030154696
CHRDL1	1.025388857	1.002373365	1.048932808	0.030416027
NR3C2	0.882165693	0.787326645	0.988428773	0.030731862
IL17RB	0.958795008	0.922419497	0.996604983	0.032982279
CDC45	0.942908559	0.893309918	0.995261032	0.032985263
GCG	1.017196705	1.001258421	1.033388700	0.034341311
AJUBA	1.095354855	1.006562312	1.191980113	0.034719811
WDR4	0.943248674	0.893260819	0.996033903	0.035465193
CCNB1	0.986749509	0.974543568	0.999108326	0.035690679
CRYAB	1.030028043	1.001890929	1.058955359	0.036291275
ARHGAP44	0.845014051	0.719943532	0.991812155	0.039344784
ADH1B	1.056282963	1.002144123	1.113346545	0.041375192
CCNA2	0.974828540	0.951169319	0.999076256	0.041983147
SRPK1	0.980350420	0.961688311	0.999374677	0.042995634
GNL3	0.983089244	0.966962682	0.999484758	0.043276128
OSBPL1A	1.108175856	1.001910012	1.225712602	0.045818190

HR: hazard ratio.